Inflammation in Acute Coronary Syndromes: Systemic, Coronary Plaque, or Myocardial Source?
نویسندگان
چکیده
منابع مشابه
Inflammation in acute coronary syndromes.
Extensive evidence supports a pathogenic role for both local and systemic inflammation in acute coronary syndromes. However, several important questions remain unanswered. Is the observed inflammatory process a precursor or a consequence of coronary plaque rupture? Is the inflammatory component of unstable coronary disease a potential therapeutic target? Finally, do infectious agents have a pat...
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Inflammation is becoming an intriguing focus of research as a possible pathogenetic component and therapeutic target in ischaemic heart disease. However, the potential links between inflammation and ischaemic heart disease are present at three levels at least. First, the inflammatory response has been known for many years to play a major role in ischaemia/reperfusion injury, and its reduction c...
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Introduction: Coronary artery disease (CAD) is among the most common, serious, chronic and life- threatening illnesses in the world. CAD represents a spectrum of conditions, with acute myocardial infarction at one end of it and silent ischemia at the other. There is growing evidence on importance of prognosis of C- reactive protein (CPR) in unstable angina and this protein is a maker of an adve...
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Acute coronary syndromes (ACS) continue to be the most common morbid condition of industrialized nations. The advent of and technical improvements in revascularization and medical therapy have led to a steady decline in mortality rates. However, many patients who suffer unstable angina or myocardial infarction require further testing and risk stratification to guide therapeutic selection and pr...
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Background—Systemic levels of myeloperoxidase predict prognosis in patients with acute coronary syndromes and are considered a marker of plaque vulnerability. It is not known whether myeloperoxidase is associated with different coronary morphologies (ie, rupture or erosion of the culprit lesion) in patients with acute coronary syndrome. Methods and Results—Twenty-five consecutive patients (aged...
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ژورنال
عنوان ژورنال: Journal of Cardiology & Cardiovascular Therapy
سال: 2015
ISSN: 2474-7580
DOI: 10.19080/jocct.2015.01.555551